If everyone did that the site would have had to close last year.
It doesn't affect the back end, just the user experience. I hate adverts so do whatever to block/remove them.
It affects the back end when I can't afford to keep the site going, which was pretty close to the case last year due to the millions of images we now host and the large amount of bandwidth cost. Thankfully there were enough Club RR people renewing that the lights stayed on in conjunction with the ad income from running these Google ads.